PHILADELPHIA–(BUSINESS WIRE)–InterVenn Biosciences, the leader in glycoproteomics, presented results today on the application of its perspectIV™ platform in COVID-19 patients, demonstrating that glycoproteomic profiles in patients with a severe course of the infection are significantly different from those who experienced an asymptomatic course of the infection. InterVenn’s proprietary perspectIV™ platform is capable of interrogating the blood glycoproteome at a depth and scale heretofore never possible, using a unique combination of mass-spectrometry and proprietary AI-powered software, opening up a whole new domain of biology to the identification of novel biomarkers and diagnostic tools for a broad range of applications.
Results were presented today at the American Society for Mass Spectrometry Conference from a study conducted including samples of patients who had been seriously ill with COVID-19, of individuals who had an asymptomatic course of COVID-19, and of other patients, as additional references, who had been diagnosed with either bacterial sepsis, common-cold coronavirus, or who were healthy controls. The study results show that there are statistically highly significant glycoproteomic profiles differentiating severe from asymptomatic COVID-19. Of interest, while a number of glycoproteomic attributes were shared between patients suffering from symptomatic COVID-19 and bacterial sepsis, likely representative of a systemic inflammatory response, a subset of glycoproteomic biomarkers were specific to severe COVID-19, potentially providing insights into specific pathological consequences of, or a particular predisposition for, a severe course of the infection.
“These results highlight yet another clinically important use application of perspectIV™ and the potential of glycoproteomics to discover new biomarkers and novel insights into pathobiology,” said Aldo Carrascoso, CEO and co-founder of InterVenn.
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About InterVenn Biosciences
InterVenn Biosciences utilizes a proprietary glycoproteomic biomarker discovery and interrogation platform based on artificial intelligence-empowered mass spectrometry for next-gen precision medicine. The company is working on developing novel predictive tests in a range of indications, including ovarian, pancreatic, liver, prostate, lung, kidney and other cancers, as well as on tests for treatment response prediction and monitoring of treatment efficacy, and disease progression.
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